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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PI4KB
All Species:
25.45
Human Site:
S258
Identified Species:
50.91
UniProt:
Q9UBF8
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBF8
NP_002642.1
816
91379
S258
K
R
E
L
P
S
L
S
P
A
P
D
T
G
L
Chimpanzee
Pan troglodytes
XP_001171600
816
91257
S258
K
R
E
L
P
S
L
S
P
A
P
D
T
G
L
Rhesus Macaque
Macaca mulatta
XP_001106422
828
92728
S270
K
R
E
L
P
S
L
S
P
A
P
D
T
G
L
Dog
Lupus familis
XP_540314
945
105487
S387
K
R
E
L
P
S
L
S
P
A
P
D
M
G
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8BKC8
816
91497
S258
K
R
E
L
P
T
L
S
P
A
P
D
T
G
L
Rat
Rattus norvegicus
O08561
816
91637
S258
K
R
E
L
P
T
L
S
P
A
P
D
T
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423394
743
82507
D231
L
L
G
A
Y
S
S
D
M
H
I
S
T
Q
R
Frog
Xenopus laevis
Q6GN16
804
90437
D246
L
R
K
L
I
L
S
D
E
L
K
P
A
H
K
Zebra Danio
Brachydanio rerio
Q49GP3
835
94040
P277
Q
R
I
R
R
E
V
P
Q
P
P
P
P
Y
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524822
1674
181956
S1075
S
P
H
T
L
S
I
S
H
R
M
Y
Q
Q
P
Honey Bee
Apis mellifera
XP_391922
1078
119863
S491
N
K
K
T
H
Q
R
S
Q
S
D
A
S
G
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P39104
1066
119905
P330
N
K
G
D
Y
I
S
P
K
G
R
N
D
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
98.1
84.2
N.A.
98.5
97.6
N.A.
N.A.
78.6
85.2
74.9
N.A.
25.7
42.1
N.A.
N.A.
Protein Similarity:
100
99.2
98.3
84.9
N.A.
99.1
98.6
N.A.
N.A.
83.4
90
82.7
N.A.
36.2
55.5
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
N.A.
13.3
13.3
13.3
N.A.
13.3
20
N.A.
N.A.
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
N.A.
13.3
20
26.6
N.A.
20
46.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
50
0
9
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
17
0
0
9
50
9
0
0
% D
% Glu:
0
0
50
0
0
9
0
0
9
0
0
0
0
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
17
0
0
0
0
0
0
9
0
0
0
59
0
% G
% His:
0
0
9
0
9
0
0
0
9
9
0
0
0
9
0
% H
% Ile:
0
0
9
0
9
9
9
0
0
0
9
0
0
0
0
% I
% Lys:
50
17
17
0
0
0
0
0
9
0
9
0
0
0
9
% K
% Leu:
17
9
0
59
9
9
50
0
0
9
0
0
0
0
59
% L
% Met:
0
0
0
0
0
0
0
0
9
0
9
0
9
0
0
% M
% Asn:
17
0
0
0
0
0
0
0
0
0
0
9
0
0
9
% N
% Pro:
0
9
0
0
50
0
0
17
50
9
59
17
9
0
17
% P
% Gln:
9
0
0
0
0
9
0
0
17
0
0
0
9
17
0
% Q
% Arg:
0
67
0
9
9
0
9
0
0
9
9
0
0
0
9
% R
% Ser:
9
0
0
0
0
50
25
67
0
9
0
9
9
0
0
% S
% Thr:
0
0
0
17
0
17
0
0
0
0
0
0
50
0
0
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
17
0
0
0
0
0
0
9
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _